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・ Topological order
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・ Topological quantum computer
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・ Topological quantum number
・ Topological rigidity
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・ Topological semigroup
・ Topological skeleton
・ Topological sorting
・ Topological space
・ Topological string theory
・ Topological tensor product
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Topologically Associating Domain
・ Topologically Integrated Geographic Encoding and Referencing
・ Topologically stratified space
・ Topologika
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・ Topologist's sine curve
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・ Topology (chemistry)
・ Topology (disambiguation)
・ Topology (electrical circuits)
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・ Topology and its Applications
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Topologically Associating Domain : ウィキペディア英語版
Topologically Associating Domain
"Topologically associating domains" (TADs) are a way of understanding the organization of mammalian genomes as being split up into "chromosome neighborhoods" within which most enhancer-promoter contact occurs. They can range in size from thousands to millions of DNA bases. TADs are separated from each other by boundary regions enriched for transfer RNA genes and for binding of the transcription factor CTCF.
==Conservation in mammalian genomes==
TADs have been reported to be relatively constant in different cell types (in stem cells and blood cells, for example).

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